|
Metabolic Syndrome X
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
A Receiver Operator Characteristic curve was used to identify the ability of adiponectin and leptin level to predict the MetS.
|
31341853 |
2019 |
|
Metabolic Syndrome X
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
The adipokines DPP-4 and leptin in the serum can influence the body fat distribution of patients with T2MD; there is an important association of DPP-4, leptin and ADPN levels with MS, which may be used as therapeutic targets for multiple metabolism disorders of T2MD.
|
29205013 |
2019 |
|
Metabolic Syndrome X
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Patients with MetS had higher levels of leptin (14 ± 12.4) compared with those without MetS (11.2 ± 9.3 vs. 7 ± 7.1 obese and normal weight without MetS, respectively; p = .002).
|
27550773 |
2017 |
|
Metabolic Syndrome X
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Low vitamin D level was associated with metabolic syndrome and high leptin level in subjects with nonalcoholic fatty liver disease: a community-based study.
|
31311491 |
2019 |
|
Metabolic Syndrome X
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Although the associations between adiponectin, leptin, resistin and metabolic abnormalities in our paediatric population were similar to those in adults, correlations of FGF21 levels with obesity, IR and MetS were the inverse of those found in adults.
|
28139438 |
2017 |
|
Metabolic Syndrome X
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
The CGC haplotype was less prevalent in subjects with the metabolic syndrome (P=0.0015) and was associated with lower waist circumference (P=0.007), lower hip circumference (P=0.023), lower body mass index (P=0.043) and lower leptin levels (P=0.028).
|
18071340 |
2008 |
|
Metabolic Syndrome X
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
The aim of this study was to compare metabolic aspects potentially associated with metabolic syndrome (MetS), in addition to serum leptin levels and sleep, according to exposure to night work among nursing staff.
|
29580071 |
2018 |
|
Metabolic Syndrome X
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
In first-degree relatives normal glucose tolerant women, fasting hyperinsulinemia, independently of the presence of metabolic syndrome, is associated with elevated IL-6 and leptin levels, suggesting an increased cardiovascular risk.
|
19685554 |
2009 |
|
Metabolic Syndrome X
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
We previously found that blood C-reactive protein (CRP), interleukin-6 (IL-6), and leptin levels were predictors of current metabolic syndrome in schizophrenia.
|
31118157 |
2019 |
|
Metabolic Syndrome X
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
In conclusion, SHBG served as a major predictor for the risk of MetS and was correlated with serum adiponectin and leptin levels that are independent of T. Further studies are needed to elucidate the true role of SHBG in the pathogenesis of MetS and possible mechanisms associated with serum adiponectin and leptin levels.
|
28577342 |
2017 |
|
Metabolic Syndrome X
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Results of this study indicate that leptin (15.92 ± 10.50 vs.9.43 ± 4.39 pg/ml, p < 0.001), L:A ratio (1.08 ± 1.06 vs.0.42 ± 0.38 pg/ml, p < 0.001), HOMA-IR, the lipid profile, and other metabolic risk factors (waist circumference (WC), waist-to-hip ratio(WHR), body mass index((BMI)), fasting plasma glucose (FPG) level and fasting plasma insulin(FPI)) were significantly higher but HDL, HDL/LDL and adiponectin level (20.55 ± 10.76 vs.30.08 ± 13.08 pg/ml, p < 0.001)were significantly lower in postmenopausal women with metabolic syndrome than in women without the syndrome (p < 0.001).
|
29410303 |
2018 |
|
Metabolic Syndrome X
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
We aimed to explore the association of <i>LEPR</i> polymorphisms with obesity, metabolic syndrome (MetS), and leptin levels in Afro-Caribbean nondiabetic subjects.
|
30807250 |
2019 |
|
Metabolic Syndrome X
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
The substantial up-regulation of leptin mRNA may be epigenetically conferred and relevant to the post-natal risk of metabolic syndrome in intrauterine growth restriction offspring with placental pathology.
|
23832168 |
2013 |
|
Metabolic Syndrome X
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Evaluation of adiponectin and leptin levels and oxidative stress in bipolar disorder patients with metabolic syndrome treated by valproic acid.
|
28875764 |
2017 |
|
Metabolic Syndrome X
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Moreover, the circulating miRNA profiles were associated with the plasma leptin level in metabolic syndrome, and miRNAs were found to be involved in hypothalamic leptin sensitivity.
|
31408957 |
2019 |
|
Metabolic Syndrome X
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
The available relatives of the same family were interviewed (DSM-IV-R) and assessed in fasting conditions for body mass index, constituent variables of the metabolic syndrome (MS), leptin levels, insulin resistance index, and single nucleotide polymorphisms (SNPs) for the leptin receptor and promoter and PPAR-γ2 genes.
|
26083812 |
2016 |
|
Metabolic Syndrome X
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Leptin levels and homeostatic model assessment (HOMA) scores were significantly higher in SLE MetS<sup>+</sup> than SLE MetS<sup>-</sup> ( p = 0.018; p = 0.04).
|
29954279 |
2018 |
|
Metabolic Syndrome X
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
In univariate analysis, we found that there was no difference between A allele carriers and noncarriers in most of the clinical characteristics of the metabolic syndrome such as body mass index (BMI), waist-to-hip ratio, plasma leptin levels, total cholesterol, HDL- and LDL-cholesterol, triglycerides, plasma fasting glucose, insulin, and homocysteine levels.
|
16202847 |
2005 |
|
Metabolic Syndrome X
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
To determine how leptin and ghrelin are expressed in the adipose tissues of obese adults undergoing gastric banding (LAGB), and to correlate tissue expression with serum concentrations and parameters of the metabolic syndrome.
|
16684122 |
2006 |
|
Metabolic Syndrome X
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
MetS-AIS patients had significantly higher leptin levels (22.71 ± 19.01 ng/ml versus 8.95 ± 9.22 ng/ml, <i>p</i> < 0.001) and lower adiponectin levels (10.71 ± 8.59 ng/ml versus 14.93 ± 10.95 ng/ml, <i>p</i> < 0.05) than non-MetS-AIS patients.
|
29225622 |
2017 |
|
Metabolic Syndrome X
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
In conclusion, the VAT and SAT leptin mRNA expressions may have a modulatory role in metabolic syndrome.
|
24297487 |
2014 |
|
Metabolic Syndrome X
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Plasma leptin levels and plasma insulin levels have been found to be elevated in patients with essential hypertension (EH) and have been suggested to be components of the metabolic syndrome.
|
10539824 |
1999 |
|
Metabolic Syndrome X
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Individual features of MetS correlated with Ob and ObR expression, but not obesity markers (BMI, waist circumference). mRNA expression of leptin (Ob) and ObR, in adipose tissue and matched tumor samples, respectively, appear to be associated with obesity status in breast cancer.
|
21574190 |
2011 |
|
Metabolic Syndrome X
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
The present results point that high leptin, resistin and ghrelin levels may be involved in the early pathophysiological process which can lead to later obesity and MeS in patients with bipolar disorder.
|
29132244 |
2018 |
|
Metabolic Syndrome X
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
The leptin and free leptin levels in plasma and SF were significantly higher in MetS-OA group than those in nMetS-OA group, while the adiponectin levels were lower (All p < 0.01).
|
29335849 |
2018 |